Introduction: Loss of follicles during initial ischemia constitutes the main limitation of ovarian tissue transplantation (OTT). We investigate the efficiency of the back muscle (B) site for human OTT using a SCID mouse xenografting model. Materials and Methods: 1) Study of vascularization and integration of OT in the grafting site during the first eight days after transplantation and Immunohistochemical staining (Anti-human and anti-mouse CD31 and CD34) to evaluate neovascularization. 2) Follicular development in B and K xenografts, three, five and seven months after grafting. Results: 1) Anti-mouse CD34 and CD31 positive endothelial cells were first noticed in B and K grafts on days 3 and 4 respectively. On day 5 all B and 70% of K grafts and on day 8, all B and K grafts were positive for mouse markers, but a higher number of murine blood vessels were counted in the B versus K grafts (14.0±1.3 versus 6.60±0.68, p
R, S., E, H., S, L., C, C., J, G., M, D., J, V. D. E., & P, D. S. (2007). Mouse Back Muscle As APromising Site For Human OvarianTissue Xenotransplantation. Cell Journal (Yakhteh), 9(supplement1), -.
MLA
Soleimani R; Heytens E; Lierman S; Cuvelier C; Gerris J; Dhont M; Van der Elst J; De Sutter P. "Mouse Back Muscle As APromising Site For Human OvarianTissue Xenotransplantation". Cell Journal (Yakhteh), 9, supplement1, 2007, -.
HARVARD
R, S., E, H., S, L., C, C., J, G., M, D., J, V. D. E., P, D. S. (2007). 'Mouse Back Muscle As APromising Site For Human OvarianTissue Xenotransplantation', Cell Journal (Yakhteh), 9(supplement1), pp. -.
VANCOUVER
R, S., E, H., S, L., C, C., J, G., M, D., J, V. D. E., P, D. S. Mouse Back Muscle As APromising Site For Human OvarianTissue Xenotransplantation. Cell Journal (Yakhteh), 2007; 9(supplement1): -.