Can Lucifer Yellow Indicate Correct Permeability of Biological Cell Membrane under An Electric and Magnetic Field?

Document Type : Short Communication

Authors

1 Department of Physics, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran

2 Department of Medical Physics, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran

3 Department of Physics, Faculty of Science, K. N. Toosi University of Technology, Tehran, Iran

10.22074/cellj.2015.501

Abstract

The effect of external magnetic and electric fields, in the range of electroporation and magnetoporation, on Lucifer Yellow (LY) fluorescence in the absence of cells is studied. Electric-field-induced quenching and magnetic field-induced increase are observed for fluorescence intensity of LY. Regard to the fact that the variation of field-induced fluorescence, even in the absence of cells, can be observed, the application of LY, as a marker, is debatable in electroporation and magnetoporation techniques.

Keywords