Is There A Limit To TheNumber Of Embryos To BeTransferred/Created For ART?



Pregnancy rate after ART (Artificial Reproductive Technology) is abusively considered to increase in proportion of the number of embryos transferred. Indeed this is only true up to less than 5 embryos, and is highly dependant on the woman’s age. Above all a policy of too many embryos transfer entails an excessively high number of multiple pregnancy, as high as 26-30%, including 3- 4% triplets. The hazards of multiple pregnancy both for mothers and offspring led several countries to limit by law the number of embryos to be created/transferred during ART. A policy of a single embryo transfer, eventually followed, in case of implantation failure, by the transfer of a cryopreserved embryo during a next cycle, has proven to be significantly as efficient as the transfer of two fresh embryos, with a drastic reduction in multiple pregnancy. The advantage of the transfer of a single embryo at the blastocyst stage is discussed. FIGO Ethics Committee recommends an embryo policy transfer achieving a singleton pregnancy.