The Effect Of Long-Term Potentiation With 25 Hz Frequency On Hippocampus Of Freely Moving Rats

Document Type : Original Article


Hysiology Department, Medical Sciences School, Tarbiat Modarres University, Tehran, Iran


Introduction: In this study the effects of long-term potentiation (LTP) on short-term plasticity (STP) were examined.
Material and Methods: Experiments were carried out on hippocampus of freely moving rats. The changes in the field potentials, which were evoked by delivering train of pulses at 25 Hz frequency, were examined before and after induction of LTP.
Results: Stp was different in potentiated synapses. LTP could potentiate only the first response.
Conclusion: The interaction of LTP with STP would be important in information processing.