Cell Therapy in Burn Repair


Stem Cells Department, Cell Sciences Research Center, Royan Institute, ACECR, Tehran, Iran


Skin replacement has been a challenging task in wound healing resulted from burn. The
application of laboratory based tissue expansion techniques is a potential solution to
the problem of surface area cover. Fortunately, considerable progress has been made
in approaches to allograft and autograft skin transplantation in order to replace skin
temporarily or permanently. Despite of this progress, development of new treatments for
burn victims are still a problem in cultured skin grafts. Hair follicles, sweat glands and other
features of normal skin are absent in cultured skin. Scientists believe that Stem cells with
unique characteristics including self renewal and differentiation potential offer a possible
way for reconstruction of some structures within the wound. So, enhanced understanding
of stem cell potentials may help develop novel therapies to overcome the problems in
wound healing.